Is tesamorelin a weight-loss drug?

No. Per FDA labeling, tesamorelin is not a weight-loss medication and should not be used to treat obesity. It is approved only for reducing excess abdominal fat in HIV-infected adults with lipodystrophy.

What is the difference between Egrifta SV and Egrifta WR?

Egrifta SV requires daily reconstitution. Egrifta WR (approved March 2025) requires less than half the administration volume and only weekly reconstitution. They have different recommended dosages and are not substitutable.

How quickly does tesamorelin work?

Fat reduction begins in weeks 1-2, with significant changes at 4-6 weeks and full benefits at 8-12 weeks. Phase 3 trials demonstrated efficacy over 26 weeks of therapy.

What is the recommended dose range for Tesamorelin?

The research dose range is 2 mg/day SC (FDA-approved dose), administered via Subcutaneous, Once daily.

peptide dosing

Tesamorelin Dosing & Reconstitution Guide

Complete dosing reference for Tesamorelin (Growth Hormone Secretagogue). Covers reconstitution, dose range, titration schedule, pharmacokinetics, and storage protocols for research use.

Dosing Protocol

Route: Subcutaneous Frequency: Once daily Dose Range: 2 mg/day SC (FDA-approved dose) Cycle Length: Ongoing; FDA-approved for chronic use in HIV-associated lipodystrophy Timing: Before bed on empty stomach

Reconstitution

Vial Size: 5mg Water Volume: 2.5mL Concentration: 2mg/mL

Timeline & Pharmacokinetics

Onset: 15–30 minutes Peak Plasma: ~15 minutes (median Tmax) Half-Life: ~26–38 minutes Steady State: 2–4 weeks of daily dosing Time to Results: 8–12 weeks for visceral fat reduction; 26 weeks in clinical trials Washout: 1–2 weeks

Storage

Lyophilized: −20 °C (−4 °F) Reconstituted: 2–8 °C (35.6–46.4 °F) Shelf Life: 28 days

Injection Sites

Abdomen

Safety & Contraindications

Safety: Common: injection site reactions (17%), arthralgia (13%), myalgia (6%), peripheral edema (6%) Headache, nausea, and flu-like symptoms reported May increase blood glucose -- monitoring recommended in diabetics

Contraindications: Pregnancy (Category X -- absolute contraindication); Active cancer or history of any tumor (benign or malignant); Pituitary gland disorder, tumor, or history of pituitary surgery

Related Products

In Stock

Tesamorelin 10mg

10mg

Application formLyophilized powder

StorageRefrigerated

Purity98%

AppearanceLyophilized powder

$64 USD

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Research Use Only. The information on this page is compiled from published research literature and is provided for educational purposes only. It does not constitute medical advice. All compounds referenced are intended for in vitro research use by qualified laboratories and institutions.